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encyclopedia of Rare Disease Annotation for Precision Medicine

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	generalized resistance to thyroid hormone

Disease ID	1059
Disease	generalized resistance to thyroid hormone
Definition	This gene plays a role in receptor signaling and regulation of transcription. It is involved in inner ear development and color vision.
Synonym	avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2 beta gene, erba beta gene, tr beta genes, erba beta genes, tr erba beta gene erba beta genes erba-beta erba-beta gene erba-beta genes erba2 gene, thrb genes, erba beta genes, erba-beta genes, thrb genes, tr beta genes, tr-beta grth nr1a2 oncogene erba2 thr1 thrb gene thrb genes thrb1 thrb2 thyroid hormone receptor beta 1 thyroid hormone receptor, beta thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) gene tr beta gene tr beta genes tr-beta gene tr-beta genes v-erb-a avian erythroblastic leukemia viral oncogene homolog 2
Orphanet	ORPHANET:3221
OMIM	OMIM:190160 OMIM:607663
UMLS	C0242988
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:4) C0007115 \| thyroid cancer \| 1 C0007115 \| thyroid ca \| 1 C0040147 \| thyroiditis \| 1 C0677607 \| hashimoto's thyroiditis \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:3) 7068 \| THRB \| OMIM;UNIPROT 29118 \| DDX25 \| OMIM 7201 \| TRHR \| UNIPROT
Inferring Gene	(Waiting for update.)
Text Mined Gene	(Waiting for update.)
Locus	Symbol \| Locus(Total Locus:1) THRB \| 3p24.2

Disease ID	1059
Disease	generalized resistance to thyroid hormone
Integrated Phenotype	HPO \| Name(Total Integrated Phenotypes:7) HP:0010655 \| Epiphyseal stippling HP:0002750 \| Delayed skeletal maturation HP:0000444 \| Convex nasal ridge HP:0000912 \| Sprengel anomaly HP:0000407 \| Sensorineural hearing impairment HP:0000768 \| Pectus carinatum HP:0000820 \| Abnormality of the thyroid gland
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:3) HP:0000872 \| Hashimoto's thyroiditis \| 1 HP:0100646 \| Thyroiditis \| 1 HP:0002930 \| Resistance to thyroid hormone \| 1

Disease ID	1059
Disease	generalized resistance to thyroid hormone
Manually Symptom	UMLS \| Name(Total Manually Symptoms:2) C0342158 \| autoimmune hypothyroidism C0154143 \| toxic multinodular goitre
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:63)
Chr	Pos	SNP_Id	RefGene	EnsemblGene	ENCODE_Factor	ENCODE_TFBS	Chromosome_interaction	GTEx_eQTL	SNP_TFBS_affinity_GWAS3D	SNP_miRNA_target_affinity_PolymiRTS	SNP_splicing_effect_Skippy	SNP_splicing_effect_MutPred_Splice	SNP_ns_protein_effect_dbNSFP	SNP_syn_effect_Silva	SNP_phosphorylation_effect_PhosSNP	PhastCons_score	PhyloP_score	GERP++_RS	Segway_state	Ancestral_allele	ESP_AF	ESP_AFR	ESP_AFR	ESP_EUR	TG_ASN	TG_AMR	TG_AFR	TG_EUR	Type	Consequence	bStatistic	EncH3K27Ac	EncH3K4Me1	EncH3K4Me3	EncNucleo	OMIM	Clinvar
3	24165541	rs6782978	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000456926,ENSG00000151090	ENST00000280696,ENSG00000151090	NA	NA	chr3,24160001,24170000,chrX,88670001,88680000,7,Hi-C	chr3,24160001,24170000,chr16,2990001,3000000,8,Hi-C	NA	LM2,1.6458	LM4,3.4865	LM6,2.94	LM100,1.406	Arnt,14.267	NA	NA	NA	NA	NA	NA	0.000	-0.224	-1.41	TF1	A	NA	NA	NA	0.230
3	24169493	rs1868573	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000456926,ENSG00000151090	ENST00000280696,ENSG00000151090	CHMM	NA	chr3,24160001,24170000,chrX,88670001,88680000,7,Hi-C	chr3,24160001,24170000,chr16,2990001,3000000,8,Hi-C	NA	Cdx1_2245,14.268	Cdx2_4272,6.7153	Hoxa11_2218,20.6132	Hoxa13_3126,5.5264	Hoxc10_2779,44.8921	NA	NA	NA	NA	NA	NA	0.000	-0.790	-4.08	GE1	T	NA	NA	NA	NA
3	24172777	rs826379	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000456926,ENSG00000151090	ENST00000280696,ENSG00000151090	NA	NA	chr3,24170001,24180000,chr11,63930001,63940000,7,Hi-C	NA	Hoxb8_3780,1.7129	Hoxc10_2779,1.5531	Hoxc9_2367,1.9261	Otx2_3441,28.128	Pitx2_2274,31.9082	NA	NA	NA	NA	NA	NA	0.002	0.155	0.476	GE0	A	NA	NA	NA	0.570	0.660
3	24173744	rs1705734	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000456926,ENSG00000151090	ENST00000280696,ENSG00000151090	NA	NA	chr3,24170001,24180000,chr11,63930001,63940000,7,Hi-C	NA	LM183,24.9863	FOXI1,1.2708	CRGAARNNNNCGA,1.9168	C/EBP,2.4921	AIRE,2.2207	NA	NA	NA	NA	NA	NA	0.000	-1.089	-5.45	L1	G	NA	NA	NA	NA	NA
3	24187084	rs826385	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000456926,ENSG00000151090	ENST00000280696,ENSG00000151090	TFP.JUN	CHMM	TFP.JUND	MCV-9	NA	NA	NA	LM14,2.2555	LM23,1.6472	LM50,1.3153	LM50,2.0843	LM58,1.8426	NA	NA	NA	NA	NA	NA	0.006	-0.310	-1.95	R2	A	NA	NA
3	24190184	rs9844739	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000456926,ENSG00000151090	ENST00000280696,ENSG00000151090	NA	NA	chr3,24190001,24200000,chr12,94780001,94790000,8,Hi-C	NA	Lhx3_3431,1.9022	Lhx9_3492,1.3032	Lmx1a_2238,1.8723	Mga1-primary,1.5221	Smp1-primary,3.3188	NA	NA	NA	NA	NA	NA	0.003	0.614	2.11	L1	G	NA	NA	NA	0.150
3	24192584	rs2683545	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000456926,ENSG00000151090	ENST00000280696,ENSG00000151090	NA	NA	chr3,24190001,24200000,chr12,94780001,94790000,8,Hi-C	NA	NA	NA	NA	NA	NA	NA	NA	0.000	0.028	0.249	R2	C	NA	NA	NA	NA	NA	NA	NA	NA
3	24204984	rs2596623	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000456926,ENSG00000151090	ENST00000280696,ENSG00000151090	NA	NA	NA	NA	Pou6f1_1731,2.7331	Pou6f1_3733,1.8823	LM6,1.4271	LM7,1.2643	LM20,1.4214	NA	NA	NA	NA	NA	NA	0.000	-0.378	-3.73	GE0
3	24211739	rs2683530	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000456926,ENSG00000151090	NA	NA	NA	NA	Alx4_1744,5.4505	Barx1_2877,1.2747	Barx2_3447,1.6695	Cart1_0997,5.6301	Gat3-primary,1.5614	NA	NA	NA	NA	NA	NA	0.033	2.169	3.38	R1	C
3	24221947	rs2683540	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000456926,ENSG00000151090	NA	NA	NA	NA	LM63,5.3042	LM85,6.6089	LM92,1.4865	LM143,1.6724	LM144,4.3817	NA	NA	NA	NA	NA	NA	0.212	-0.244	-2.13	R1	T
3	24230196	rs1667739	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000456926,ENSG00000151090	NA	NA	chr3,24230001,24240000,chr21,15740001,15750000,6,Hi-C	chr3,24230001,24240000,chr4,132860001,132870000,12,Hi-C	NA	Dobox5_3493,1.3019	Ndt80-primary,1.5783	Obox5_2284,1.2955	Obox5_3963,1.3396	Srd1-primary,2.3056	NA	NA	NA	NA	NA	NA	0.009	1.106	2.77	R1
3	24251816	rs6800891	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	chr3,24250001,24260000,chr2,88190001,88200000,54,Hi-C	chr3,24250001,24260000,chr12,64540001,64550000,5,Hi-C	NA	Mga1-primary,2.2625	Sfl1-DBD-primary,2.0772	LM27,1.3283	LM31,3.3959	LM62,3.4897	NA	NA	NA	NA	NA	NA	0.000	-0.209	-0.889
3	24254517	rs7632417	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	MCV-22	NA	chr3,24250001,24260000,chr2,88190001,88200000,54,Hi-C	chr3,24250001,24260000,chr12,64540001,64550000,5,Hi-C	NA	LM129,1.8997	LM129,1.4003	Spz1,1.9019	ARR10,1.4557	GKCGCNNNNNNNTGAYG,1.9089	NA	NA	NA	NA	NA	NA	0.000	-0.927	-5.24
3	24255079	rs17014338	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	chr3,24250001,24260000,chr2,88190001,88200000,54,Hi-C	chr3,24250001,24260000,chr12,64540001,64550000,5,Hi-C	NA	LM28,3.5686	LM33,1.671	LM50,1.2998	LM68,1.78	LM84,3.8112	NA	NA	NA	NA	NA	NA	0.000	-2.012	-7.6
3	24267140	rs826223	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	Gsh2_3990,2.7218	Hoxa1_3425,3.9754	Hoxa2_3079,3.2698	Hoxa5_3415,4.7318	Hoxa6_1040,4.4445	NA	NA	NA	NA	NA	NA	0.001	0.200	0.734	R4
3	24268436	rs826221	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	LM6,3.2175	LM78,3.6763	LM104,2.7911	LM110,1.4488	LM138,1.5726	NA	NA	NA	NA	NA	NA	0.000	-0.066	-0.584	GE0
3	24269690	rs826218	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	Spz1,2.2239	CGGAARNGGCNG,2.2006	AGCYRWTTC,10.3958	RRCCGTTA,78.7324	GATA-1,8.0418	NA	NA	NA	NA	NA	NA	0.000	-0.138	-1.11	GE1
3	24270796	rs1466122	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	LM177,1.935	LM213,2.4036	dl_1,1.765	FOXF2,1.3799	TMTCGCGANR,47.9824	NA	NA	NA	NA	NA	NA	0.000	-3.103	-6.58	R1
3	24270970	rs4858593	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000416811,ENSG00000151090	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	LM12,8.0815	LM40,4.4476	LM41,4.7805	LM48,2.4797	LM51,3.2312	NA	NA	NA	NA	NA	NA	0.000	-0.279	-1.6	TF1
3	24271599	rs7619754	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	LM31,3.4385	LM43,1.6873	LM177,2.9309	LM195,2.0477	HMG-1,1.4237	NA	NA	NA	NA	NA	NA	0.000	0.202	0.858	R4	A
3	24271657	rs9874037	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	RSRFC4,1.2918	RSRFC4,1.3525	Evi-1,1.4067	MEF-2,1.2795	TCF11:MafG,2.8296	NA	NA	NA	NA	NA	NA	0.000	-0.509	-2.09	GE1	C
3	24271828	rs1449874	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	LM32,1.5641	LM140,1.9398	LM166,2.4006	LM174,1.7156	LM183,4.043	NA	NA	NA	NA	NA	NA	0.019	0.683	1.81	R1	C
3	24273854	rs4858594	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	Aft1-primary,2.8703	Bsx_3483,1.6042	Dlx2_2273,3.9337	Dlx3_1030,1.4099	Dlx4_3488,1.3975	NA	NA	NA	NA	NA	NA	0.001	0.412	1.34	GE0	A
3	24277179	rs9829876	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	TFP.FOSL2	MCV-1	NA	NA	NA	Dlx3_1030,1.4893	Dlx4_3488,1.4578	Duxl_1286,1.5989	Hoxa7_2668,1.2754	Hoxc6_3954,3.6023	NA	NA	NA	NA	NA	NA	0.000	0.034	0.263	TF2
3	24281488	rs12386345	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	chr3,24280001,24290000,chrX,91950001,91960000,35,Hi-C	NA	LM3,2.5113	LM11,3.3055	LM24,2.4616	LM26,1.5935	LM54,2.3755	NA	NA	NA	NA	NA	NA	0.000	-0.155	-0.751	GE0	G
3	24284794	rs1505298	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	chr3,24280001,24290000,chrX,91950001,91960000,35,Hi-C	NA	LM69,1.5812	LM73,1.3546	LM124,3.2558	LM129,3.2845	LM169,8.2281	NA	NA	NA	NA	NA	NA	0.000	0.393	1.64	TF2	T
3	24306302	rs826230	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	TFP.CTCF	TFP.RAD21	TFP.SMC3	TFP.ZNF143	TFP.EGR1	MCV-97	NA	NA	NA	LM117,3.0778	LM117,3.7631	LM141,3.3351	LM203,1.4461	LM206,3.4113	NA	NA	NA	NA	NA	NA
3	24306831	rs826231	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	TATA,1.7551	neural-restr.-silencer-element,5.2554	Pax-4,1.5364	NKX6-1,15.3065	TCF-4,1.7131	NA	NA	NA	NA	NA	NA	0.000	-0.877	-3.95	R4	G
3	24307693	rs862247	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	LM117,1.8845	LM187,4.1517	Broad-complex_4,5.3571	FOXF2,1.3321	HMG-IY,10.6271	NA	NA	NA	NA	NA	NA	0.000	-0.232	-1.42	GE0	C
3	24314612	rs826236	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	TFP.FOXA2	TFP.FOXA1	TFP.JUND	TFP.JUN	NA	NA	NA	LM3,12.8317	LM8,11.7071	LM8,1.7609	LM85,3.6426	LM88,1.4274	NA	NA	NA	NA	NA	NA	0.068	0.437
3	24316463	rs826238	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	Cgd2_3490,1.5202	Cgd2_3490,5.6136	Cha4-primary,3.1736	Gat4-primary,2.6604	Hdx_3845,2.7802	NA	NA	NA	NA	NA	NA	0.002	-0.080	-0.371	GE0	T
3	24317591	rs826240	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000513057,ENSG00000250051	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	LM80,1.9939	LM87,16.6611	LM89,1.2645	LM128,3.7299	LM131,11.9995	NA	NA	NA	NA	NA	NA	0.066	1.025	2.6	R2	G
3	24328678	rs1827736	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	chr3,24320001,24330000,chr1,48280001,48290000,4,Hi-C	NA	LM10,1.336	LM12,4.5854	LM27,1.7816	LM39,1.9135	LM63,6.5049	NA	NA	NA	NA	NA	NA	0.007	0.155	0.812	GE0	G	NA
3	24330283	rs1868575	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	LM53,3.2294	LM65,2.6728	LM172,4.8716	LM172,3.9808	LM178,1.2879	NA	NA	NA	NA	NA	NA	0.000	0.118	0.502	L1	A	NA
3	24336162	rs1158265	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	LM3,3.338	LM14,1.7677	LM17,7.1314	LM49,3.6193	LM89,2.81	NA	NA	NA	NA	NA	NA	0.009	0.041	0.143	GE1	T	NA
3	24337914	rs9830674	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	MCV-5	NA	NA	NA	Barx1_2877,1.4633	Dlx3_1030,1.7285	Dlx4_3488,2.5466	Dlx5_3419,1.7871	Matalpha2-primary,1.3439	NA	NA	NA	NA	NA	NA	0.000	-0.669	-4.18	GE1	T	NA
3	24339734	rs2167115	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	0.000	-0.037	-0.0395	L1	G	NA	NA	NA	NA	NA
3	24340817	rs4858603	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	TFP.GATA1	TFP.STAT3	NA	NA	NA	Cgd2_3490,1.2596	Hdx_3845,3.3089	Hmbox1_2674,4.1325	Phd1-FL-primary,5.484	Six1_0935,1.3236	NA	NA	NA	NA	NA	NA	0.000	-0.213	-1.74	GE0	A
3	24343330	rs1505307	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	Duxl_1286,1.3965	Hal9-primary,21.6028	Hal9-primary,20.3421	Hmbox1_2674,1.3104	Rtg3-primary,4.1133	NA	NA	NA	NA	NA	NA	0.000	-1.135	-4.68	C1	C	NA
3	24345776	rs1505283	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	LM66,1.4972	LM151,2.0728	LM163,6.134	LM167,1.7842	LM211,1.9746	NA	NA	NA	NA	NA	NA	0.000	-0.135	-1.05	F1	A	NA
3	24346109	rs12485694	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	Irx3_0920,1.7085	Irx4_2242,1.7745	Lhx4_1719,2.077	Pdr1-DBD-primary,1.3725	Six1_0935,1.3236	NA	NA	NA	NA	NA	NA	0.008	-0.074	-0.742	R2	A	NA
3	24346981	rs9850879	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	LM33,3.0299	LM38,11.9756	LM44,4.5	LM46,5.9033	LM49,9.0277	NA	NA	NA	NA	NA	NA	0.000	-0.871	-5.23	GM0	A	NA
3	24350811	rs9310736	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	chr3,24350001,24360000,chr13,96490001,96500000,6,Hi-C	NA	LM206,2.5919	NA	NA	NA	NA	NA	NA	0.046	1.960	3.63	R1	A	NA	NA	NA	NA	NA
3	24351642	rs10510543	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	chr3,24350001,24360000,chr13,96490001,96500000,6,Hi-C	NA	LM59,1.9473	LM75,33.861	LM102,1.6726	LM190,2.3366	LM202,1.7177	NA	NA	NA	NA	NA	NA	0.818	2.413	4.88	F0	T	NA
3	24351871	rs7622481	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	chr3,24350001,24360000,chr13,96490001,96500000,6,Hi-C	NA	Alx4_1744,5.676	Cart1_0997,2.5964	Cart1_1275,2.3261	Hoxa4_3426,4.7051	Hoxa7_2668,5.8067	NA	NA	NA	NA	NA	NA	0.000	-0.354	-2.6	GE0	T	NA
3	24355634	rs1505297	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	chr3,24350001,24360000,chr13,96490001,96500000,6,Hi-C	NA	LM30,2.0185	LM41,2.1471	LM65,3.1793	LM98,3.4734	LM142,3.3277	NA	NA	NA	NA	NA	NA	0.000	-0.049	-0.309	GE0	T	NA
3	24357082	rs7610039	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	MCV-2	NA	chr3,24350001,24360000,chr13,96490001,96500000,6,Hi-C	NA	LM9,1.3954	LM20,4.1594	LM137,4.2598	Foxa2,4.6462	GKCGCNNNNNNNTGAYG,14.8794	NA	NA	NA	NA	NA	NA	0.049	0.335	1.59	TF1	T	NA
3	24357243	rs7640580	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	chr3,24350001,24360000,chr13,96490001,96500000,6,Hi-C	NA	Dlx2_2273,1.3246	Hoxa6_1040,2.1423	Hoxc8_3429,2.1828	Hoxd3_1742,1.4177	Vax1_3499,1.2937	NA	NA	NA	NA	NA	NA	0.023	2.164	4.17	GE1	A	NA
3	24357286	rs7610222	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	chr3,24350001,24360000,chr13,96490001,96500000,6,Hi-C	NA	LM4,26.5126	LM15,1.3546	LM17,1.9624	LM49,1.5994	LM78,2.3195	NA	NA	NA	NA	NA	NA	0.000	-0.333	-2.75	GE1	T	NA
3	24357332	rs12639035	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	chr3,24350001,24360000,chr13,96490001,96500000,6,Hi-C	NA	Dlx3_1030,1.5933	Dlx5_3419,1.4305	Emx2_3420,1.8963	En2_0952,1.4187	Evx1_3952,1.466	NA	NA	NA	NA	NA	NA	0.000	0.039	0.241	GE1	G	NA
3	24369366	rs17014539	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	Fkh1-FL-primary,22.3825	Fkh2-primary,21.649	Sfl1-DBD-primary,1.3071	LM76,1.7723	LM131,2.5845	NA	NA	NA	NA	NA	NA	0.000	0.286	0.968	GE0	G	NA
3	24370875	rs9812034	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	chr3,24370001,24380000,chr9,43770001,43780000,291,Hi-C	chr3,24370001,24380000,chr3,24880001,24890000,8,Hi-C	chr3,24370001,24380000,chr8,58930001,58940000,6,Hi-C	NA	Dobox4_3956,1.7939	Six1_0935,3.9957	Six2_2307,2.3399	Six3_1732,2.152	Six6_2267,1.4142	NA	NA	NA	NA	NA	NA	0.000	-0.567	-3.2	TF1
3	24379744	rs7609823	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	chr3,24370001,24380000,chr9,43770001,43780000,291,Hi-C	chr3,24370001,24380000,chr3,24880001,24890000,8,Hi-C	chr3,24370001,24380000,chr8,58930001,58940000,6,Hi-C	NA	Dlx2_2273,1.5682	En2_0952,1.5115	Gbx1_2883,1.9276	Gbx1_2883,1.8668	Yer130c-primary,2.0156	NA	NA	NA	NA	NA	NA	0.000	-0.367	-2.56	R4
3	24384005	rs9833191	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	TFP.TAL1	CHMM	MCV-1	NA	NA	NA	Rds1-primary,1.6107	Ydr520c-primary,3.6459	LM1,34.11	LM1,1.2643	LM6,1.6068	NA	NA	NA	NA	NA	NA	0.000	-1.266	-5.48	GS
3	24390258	rs7619474	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	LM85,2.577	LM85,2.3188	LM102,1.479	LM189,2.0264	LM217,1.5094	NA	NA	NA	NA	NA	NA	0.002	0.056	0.222	GM0	C	NA
3	24403210	rs6781111	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	TFP.MAFK	MCV-1	NA	NA	NA	LM12,3.961	LM17,2.7912	LM113,1.6843	LM133,1.4579	LM173,2.6382	NA	NA	NA	NA	NA	NA	0.000	0.175	0.701	R4	T
3	24410415	rs6550859	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	TFP.SPI1	TFP.JUND	TFP.JUN	NA	NA	NA	LM145,2.1648	LM211,1.6427	LM216,1.3674	LM229,1.6264	Pax5,4.6009	NA	NA	NA	NA	NA	NA	0.006	0.559	1.62	R4
3	24413479	rs11919155	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	Aft1-primary,15.1175	Dlx5_3419,1.3193	Gln3-primary,1.5849	Hoxb13_3479,2.6137	Nkx1-2_3214,1.8997	NA	NA	NA	NA	NA	NA	0.000	0.149	0.603	TF1	C	NA
3	24419005	rs12638970	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	MCV-11	NA	NA	NA	Hdx_3845,1.459	Met32-primary,2.9532	LM1,7.9314	LM1,1.5172	LM9,3.3082	NA	NA	NA	NA	NA	NA	0.000	-0.705	-3.12	GM0	T	NA
3	24508021	rs3903470	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	Aft1-primary,1.8639	Gbx1_2883,1.372	VBP,1.4609	HLF,1.7395	NA	NA	NA	NA	NA	NA	0.000	-0.169	-0.574	GE1	C	NA	NA
3	24511270	rs982952	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	Fkh1-FL-primary,1.4512	Fkh2-primary,1.2869	Hlxb9_3422,1.5228	Hmx2_3424,1.7987	Hmx3_3490,1.5393	NA	NA	NA	NA	NA	NA	0.000	-0.295	-1.44	GE0	G	NA
3	24512956	rs4353759	NM_001128176,THRB	NM_000461,THRB	NM_001128177,THRB	ENST00000396671,ENSG00000151090	ENST00000356447,ENSG00000151090	ENST00000416420,ENSG00000151090	ENST00000413780,ENSG00000151090	ENST00000447875,ENSG00000151090	ENST00000415021,ENSG00000151090	ENST00000453729,ENSG00000151090	ENST00000431815,ENSG00000151090	ENST00000447414,ENSG00000151090	ENST00000428492,ENSG00000151090	ENST00000418247,ENSG00000151090	NA	NA	NA	NA	LM14,1.3962	LM65,2.0702	LM68,3.9921	LM96,1.263	LM180,1.3888	NA	NA	NA	NA	NA	NA	0.000	-1.635	-5.46	GE0	A	NA
11	125788985	rs516482	NM_013264,DDX25	ENST00000533033,ENSG00000255027	ENST00000525943,ENSG00000109832	ENST00000263576,ENSG00000109832	ENST00000530414,ENSG00000109832	ENST00000526875,ENSG00000109832	NA	NA	NA	NA	Dmbx1_2277,1.9699	Hoxa13_3126,5.6807	Hoxc12_3480,5.8869	Hoxc13_3127,2.3934	Hoxd10_2368,1.8555	NA	NA	NA	NA	NA	NA	0.000	0.268	0.225	R2	A	NA	NA	NA	0.690	0.680	0.730	0.670	0.690	Transcript

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:4)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0000820	Abnormality of the thyroid gland	MP:0020010	decreased bone mineral density of femur	reduction in the quatitative measurment value of mineral content of bone in the long bone of the thigh
HP:0000407	Sensorineural hearing impairment	MP:0006330	syndromic hearing impairment	hearing impairment that is usually associated with malformations of the external ear and other inherited signs and symptoms
HP:0000444	Convex nasal ridge	MP:0004471	short nasal bone	reduced length of either of two rectangular bone plates forming the bridge of the nose
HP:0002750	Delayed skeletal maturation	MP:0003379	absent sexual maturation	failure to initiate pubertal changes that result in achievement of full sexual capacity

Mapped by homologous gene(Total Items:7)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0000768	Pectus carinatum	MP:0020254	decreased collagen level	decreased level of the main structural protein of the various connective tissues in animals
HP:0000407	Sensorineural hearing impairment	MP:3000003	abnormal Ebner's gland morphology	any structural anomaly of the serous salivary glands which reside adjacent to the moats surrounding the circumvallate and foliate papillae just anterior to the posterior third of the tongue, anterior to the terminal sulcus; these exocrine glands secrete l
HP:0002750	Delayed skeletal maturation	MP:0020169	increased thyroid gland weight	higher than average weight of the thyroid gland
HP:0000912	Sprengel anomaly	MP:0020169	increased thyroid gland weight	higher than average weight of the thyroid gland
HP:0010655	Epiphyseal stippling	MP:0020254	decreased collagen level	decreased level of the main structural protein of the various connective tissues in animals
HP:0000820	Abnormality of the thyroid gland	MP:0020169	increased thyroid gland weight	higher than average weight of the thyroid gland
HP:0000444	Convex nasal ridge	MP:0020254	decreased collagen level	decreased level of the main structural protein of the various connective tissues in animals

Disease ID	1059
Disease	generalized resistance to thyroid hormone
Case	(Waiting for update.)